Can't sleep after drinking coffee? It's all genetics

Some people can sleep soundly even if they drink coffee before going to bed, but some people are not like this. As long as they drink coffee before going to bed (or even in the afternoon), it will be difficult for them to fall asleep. They may lie in bed for several hours and still cannot fall asleep. The quality of sleep is greatly affected. A study in the United States found that the reason for such differences in people's coffee drinking may be due to genes.

Everyone reacts to coffee differently

Marilyn Conaris, an associate professor of preventive medicine at Northwestern University Feinberg School of Medicine, said that everyone's reaction to coffee is different, and there may be other factors besides caffeine itself that cause such differences. The study was conducted on about 10,000 Europeans and reached the above conclusion. The results of the study have been published in the journal Human Molecular Genetics.

Genes affect the rate at which caffeine is metabolized

In the past, the research team found that genetic variation is closely related to coffee drinking behavior. In this study, the researchers analyzed the changes in chemical concentrations in the blood of coffee drinkers and compared the genetic variation information. The results showed that some genetic variation seems to reduce the concentration of caffeine-related chemicals in the body, which means that these people metabolize caffeine faster. This type of genetic variation is also related to higher coffee intake.

The research team also found that there is a gene related to coffee metabolism, blood sugar metabolism, and lipid metabolism. However, Conaris pointed out that although the research team discovered this phenomenon, they do not know how this gene interacts with caffeine metabolism and coffee drinking behavior. These genes are also related to some health conditions, and it is worth conducting further research in the future to explore the mechanisms behind them.

The study authors said that in the past many people believed that everyone reacts the same way when drinking coffee, but this study overturned this idea.

Drinking coffee in divided doses is more effective in refreshing you

Harvard Medical School in the United States pointed out that studies have shown that when you are sleep deprived and want to rely on coffee to wake you up, it is best to drink coffee several times, a little each time, rather than drinking a lot of coffee at once. For example, if you are used to drinking 16 ounces (about 453.6 grams) of coffee in the morning, you can divide the coffee into 2-3 ounces (about 56.7 grams to 85 grams) as a portion, and drink a little every hour, which will have a better effect on refreshing. The key point is that you should drink coffee in moderation. Drinking too much coffee is not good.

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