What are the benefits and harms of the coffee you drink every day besides refreshing?

Drinks such as black tea, green tea, cola, and Red Bull also contain caffeine, but coffee has the highest caffeine content.

Caffeine can stimulate the central nervous system. This effect begins fifteen minutes after consuming a caffeinated beverage and can last up to six hours. The main effect of caffeine is to increase alertness and reduce drowsiness.

But regular or excessive coffee intake can lead to short-term or long-term complications, and what is excessive, such as more than 6 cups of brewed coffee (not instant) per day, may cause more side effects. These include difficulty concentrating, insomnia, muscle tremors, rapid heartbeat, involuntary shaking, heartburn, nervousness and irritability.

What are the pharmacokinetics of caffeine?

The half-life of caffeine actually varies from person to person, depending on external factors such as age, weight, pregnancy status, medication intake and liver health. In healthy adults, the half-life is about 5-6 hours, while in heavy smokers, the half-life is reduced by half, but during pregnancy, the half-life may increase by 15 hours.

Caffeine is primarily processed or metabolized in the liver via the cytochrome P450 oxidase system and broken down into three metabolic dimethylxanthines. These include:

Paraxanthine (formation 84%), breaks down fats, increases the glycerol and fat content in the blood.

Theobromine (form 12%), which dilates blood vessels and has a diuretic effect, increasing urination.

Theophylline (form 4%), which dilates the airways and is used to treat asthma.

These metabolites are then further broken down and excreted in the urine.

Caffeine crosses the blood-brain barrier, which is designed to separate the brain from the blood. Once inside the brain, caffeine blocks the effects of adenosine, which plays an important role in energy transfer and promoting sleep.

So if you drink coffee normally, it is actually beneficial, but you must not drink too much.

Excessive coffee consumption may cause the following symptoms.

• irritability
• Suppress appetite
• Insomnia
• Dizziness
• Thirsty
• Redness of the skin
• Cold sweat
• Increased heart rate and palpitations
• High blood sugar
• trouble breathing
• Tremor
• Heartburn
• stomach ache
• Nausea and vomiting
• diarrhea
• Increased urination
• Ketones in urine

Having said so much, I haven’t talked about its benefits yet. For those who like to drink it, it is still very good.

• Caffeine can improve concentration and working memory
• Caffeine can enhance physical performance and reduce the perception of muscle pain
• May relieve pain in some people with headaches (useful for those with vasoconstriction)
• Research suggests that regular, moderate caffeine intake may protect against gallstones.
• Caffeine may also play a preventive role in the development of Parkinson's disease and Alzheimer's disease.

Moderate coffee consumption has more benefits than disadvantages for health, helping to reduce the risk of cardiovascular disease, cancer, non-alcoholic fatty liver disease, cirrhosis, and also reducing the risk of death.

It can also relieve some headaches. Many headache patients say that drinking Red Bull relieves headaches, which is also because Red Bull contains caffeine.

Drinking 3 cups of coffee a day can reduce the risk of coronary heart disease by 19%, the risk of death from stroke by 30%, and the risk of cancer by 18%. The disease with the greatest reduction in risk is cirrhosis. Drinking coffee, no matter how much, can reduce the risk of cirrhosis by 39%.

For people with high blood pressure or liver problems, it is not recommended to drink a lot of coffee or caffeinated drinks, but tea is acceptable. I drink tea regularly, in small amounts and multiple times.

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